Searchable abstracts of presentations at key conferences in endocrinology

ea0090p253 | Thyroid | ECE2023

Interplay between thyroid, amiodarone and heart - case presentation

Hrabar Mirna , Matijaca Ana

Background: Amiodarone is a commonly used antiarrhythmic drug, but because of its abundance with iodine and a direct toxic effect on the thyroid, it can have side effects like hypo- and hyperthyroidism. There are two types of amiodarone-induced thyrotoxicosis (AIT). We present a case which demonstrates the importance of timely diagnosis and appropriate treatment of amiodarone-induced thyrotoxicosis in patients with serious cardiac comorbidities.Case pres...

ea0090ep944 | Reproductive and Developmental Endocrinology | ECE2023

Late-discovered mosaic Klinefelter syndrome with severe osteoporosis and obesity

Šamle Ivona , Andric Jelena , Hrabar Mirna , Pandzic Jaksic Vlatka

Background: Bone mineral density measurement sometimes reveals osteoporosis that is a consequence of undiagnosed or neglected long-standing health disorders. These secondary causes of osteoporosis should be carefully investigated, especially in men.Case Presentation: A 63-year-old male complained of back pain and was referred to endocrinology clinic due to a poor densitometry finding indicating osteoporosis. He presented with severe obesity (body mass in...

ea0090p532 | Thyroid | ECE2023

Transition from hypothyroidism to hyperthyroidism following R-CHOP treatment in mantle cell lymphoma patient

Zrilic Vrkljan Anamarija , Andric Jelena , Hrabar Mirna , Šamle Ivona , Marusic Srecko , Pandzic Jaksic Vlatka

The most common cause of primary hypothyroidism is Hashimoto’s disease, while the most common cause of hyperthyroidism is Graves’ disease; both conditions are autoimmune diseases. In clinical practice, the switch from hypothyroidism to hyperthyroidism is a rare phenomenon. So far, the etiology and mechanisms of conversion have not been determined. We present a case where we believe the monoclonal antibody rituximab was the primary cause of transition. A 58-year-old m...

ea0090ep935 | Reproductive and Developmental Endocrinology | ECE2023

Testosterone therapy in chronic liver disease

Andric Jelena , Šamle Ivona , Hrabar Mirna , Bozin Tonci , Pandzic Jaksic Vlatka

Background: Several clinical features of chronic liver disease, such as sarcopenia, anaemia, low bone mass and gynecomastia are similar as manifestation of hypogonadism. Decreased testosterone levels are common in patients with severe liver disease and are associated with worse clinical outcomes and mortality.Case Presentation: A 33-year-old patient was admitted to the hospital due to severe alcoholic hepatitis. He was in poor general condition, icteric,...

ea0090p593 | Calcium and Bone | ECE2023

Densitometry misinterpretation leading to unnecessary denosumab prescription

Hrabar Mirna , Andrić Jelena , Šamle Ivona , Pandžić Jakšić Vlatka

Background: Bone mineral density (BMD) measurement is an important tool for fracture risk assessment, but should be used with awareness of its performance and analysis pitfalls.Case Presentation: A 59-year-old patient underwent her first densitometry as part of a routine medical check-up. She had no previous fractures and no risk factors that could impair bone health. The results showed that her BMD was in the range of low bone mass. Four years later, de...